Xin Bu Selected Research

Discoidin Domain Receptor 2

1/2020	Blockade of Discoidin Domain Receptor 2 as a Strategy for Reducing Inflammation and Joint Destruction in Rheumatoid Arthritis Via Altered Interleukin-15 and Dkk-1 Signaling in Fibroblast-Like Synoviocytes.
11/2019	Deletion of discoidin domain receptor 2 attenuates renal interstitial fibrosis in a murine unilateral ureteral obstruction model.
1/2018	The pronounced high expression of discoidin domain receptor 2 in human interstitial lung diseases.
10/2016	Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis.
2/2015	The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization.
12/2014	Discoidin domain receptor 2 (DDR2) promotes breast cancer cell metastasis and the mechanism implicates epithelial-mesenchymal transition programme under hypoxia.
3/2014	A host deficiency of discoidin domain receptor 2 (DDR2) inhibits both tumour angiogenesis and metastasis.

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Xin Bu Research Topics

Disease

8	Neoplasms (Cancer) 01/2022 - 02/2015
3	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 10/2018
3	Neoplasm Metastasis (Metastasis) 01/2018 - 03/2014
2	Inflammation (Inflammations) 01/2020 - 01/2019
2	Arthritis (Polyarthritis) 01/2020 - 01/2018
2	Fibrosis (Cirrhosis) 11/2019 - 10/2016
1	Glioma (Gliomas) 01/2021
1	Rheumatoid Arthritis 01/2020
1	Melanoma (Melanoma, Malignant) 01/2020
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2019
1	Ureteral Obstruction 11/2019
1	Chronic Renal Insufficiency 11/2019
1	Myocardial Infarction 01/2019
1	Idiopathic Pulmonary Fibrosis 01/2018
1	Lung Diseases (Lung Disease) 01/2018
1	Stomach Neoplasms (Stomach Cancer) 01/2018
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2018
1	Experimental Arthritis 01/2018
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2015
1	Choroidal Neovascularization 02/2015
1	Lymphatic Metastasis 12/2014
1	Hypoxia (Hypoxemia) 12/2014
1	Breast Neoplasms (Breast Cancer) 12/2014
1	Epilepsy (Aura) 01/2011

Drug/Important Bio-Agent (IBA)

7	Discoidin Domain Receptor 2IBA 01/2020 - 03/2014
6	CollagenIBA 01/2020 - 03/2014
4	Biological ProductsIBA 01/2021 - 02/2019
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2011
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 06/2015
3	Messenger RNA (mRNA)IBA 10/2018 - 01/2018
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2016 - 03/2014
2	Fibrillar CollagensIBA 01/2020 - 10/2016
2	Small Interfering RNA (siRNA)IBA 10/2018 - 10/2016
2	Phosphotransferases (Kinase)IBA 01/2018 - 10/2016
1	EnzymesIBA 01/2022
1	Temozolomide (Temodar)FDA LinkGeneric 01/2021
1	Glutamine (L-Glutamine)FDA Link 01/2020
1	Interleukin-15 (Interleukin 15)IBA 01/2020
1	LuciferasesIBA 01/2020
1	Long Noncoding RNAIBA 12/2019
1	Calcium DobesilateIBA 11/2019
1	Hydroxyproline (4 Hydroxyproline)IBA 11/2019
1	salicylhydroxamic acid (SHAM)IBA 11/2019
1	Fatty Acids (Saturated Fatty Acids)IBA 02/2019
1	Interleukin-10 (Interleukin 10)IBA 01/2019
1	Notch ReceptorsIBA 10/2018
1	Complementary DNA (cDNA)IBA 10/2018
1	Tyrosine (L-Tyrosine)FDA Link 01/2018
1	Tyrosine Kinase InhibitorsIBA 01/2018
1	Dasatinib (BMS 354825)FDA Link 01/2018
1	Collagen ReceptorsIBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Imatinib Mesylate (Gleevec)FDA Link 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2015
1	Cadherins (E-Cadherin)IBA 12/2014
1	herminIBA 01/2011

Therapy/Procedure

1	Therapeutics 01/2021
1	Transplantation 01/2019
1	Lasers (Laser) 02/2015